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TB

TB is caused by Mycobacterium tuberculosis and spread by release of droplet nuclei from the lungs of TB infected individuals.


Fever, cough up (sometimes with blood), sweating, loss of appetite, loss of weight, and fatigue are general symptoms of TB disease. Untreated TB is often fatal, especially in persons with HIV infections. Standard treatment can lead to cure of TB disease, also in HIV-infected persons. Every year, almost 9 million new TB infections are reported while 1.9 million death cases occur due to TB.

TB Diagnotics


While the required drugs would be available, the treatment strategies in the fight against TB are suffering from the bottleneck of dedicated and suitable diagnostic tools. Among the three „global killer diseases", TB is the most difficult for making a laboratory diagnosis.


In resource-limited settings, TB is diagnosed by using sputum smears with microscopy. Fluorescence based microscopic techniques have shown to be much more sensitive than transmitted light microscopy, where M.tuberculosis bacilli in a significant number of cases are not seen, but neither conventional fluorescence nor usual light microscopes (prohibitive prices of USD 15,000-25,000) for high sensitivity TB testing are available in most labs of resource-poor countries. Partec Essential Healthcare is now offering the uniquely portable and battery-operated CyScope® TB for transmitted light and fluorescence microscopy featuring traditionally superior engineering quality of German manufacturing in highest sensitivity optical systems and a most modern high power LED technology. 


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TB and HIV


TB is the most common opportunistic infection in persons living with HIV/AIDS (PLWHA).


Many AIDS patients show previously undiagnosed, untreated, and potentially contagious TB. In total, approximately 13-14 million - or 1/3 - of all HIV-infected individuals are coinfected with TB. The risk of developing TB disease doubles in the first year after becoming HIV-infected and gets progressively higher over time. TB is a leading cause of death among PLWHA.

Geographic Distribution of Tuberculosis


Notified TB (new and relapse) per 100.000 people

New TB cases per year:

9 million

TB deaths per year:

1.6 million